100 workshop registrants!
July 28th, 2020
We have over 100 people registered for our Footprinting workshop at the ACA conference this Friday! Apparently In the era of Zoom, workshops are more popular than ever. Hope to see you there.......  Read More
by Corie Ralston
ACA Workshop Planned - July 31st
July 3rd, 2020
We've got a great lineup planned for our workshop at the ACA meeting later this month. ...  Read More
by Corie Ralston
Video tutorials
June 25th, 2020
We plan to make a series of video tutorials for the footprinting experiment, and here are the first two. These were presentations that we gave as part of the PMI workshop in June 2020:Overview of the ...  Read More
by Corie Ralston
PMI Workshop Coming Up
June 15th, 2020
Sayan, Line and I will be attending (via Zoom) the upcoming Protein Metrics "Biopharma Series from home" workshop on June 23 and 24. Line and I pre-recorded presentations on X-ray footprinting and dat...  Read More
by Corie Ralston
The New Beamline Normal
June 2nd, 2020
Berkeley Lab is taking social distancing requirements very seriously. We had a chance to access the footprinting beamline last week, and here is Sayan in the hutch. We are all getting used to working ...  Read More
by Corie Ralston
Matt's thesis defense
April 24th, 2020
Matthew Rosi gave his master's thesis defense today at Sonoma State (via Zoom, of course, because of COVID-19). Below is one slide from his presentation, which covered the development of the new jet i...  Read More
by Corie Ralston
Research on hold
March 29th, 2020
Well, like most everyone else, we have been shut down by COVID-19. Our new mirror tank and stand did arrive right before Berkeley Lab went into curtailment mode. But the ALS ring is down now, and all ...  Read More
by Corie Ralston
Focusing mirror to arrive soon
February 26th, 2020
The company ADC is almost ready to ship the new mirror tank for our focusing mirror. This will be installed in beamline 3.3.1, and will provide significantly higher brightness for the footprinting exp...  Read More
by Corie Ralston
More laser footprinting fun
February 23rd, 2020
We went back to Adam's laser lab to try out footprinting, this time on an actual protein - Cytochrome C. Below are Line and Adam in the midst of sample preparation and exposure, but barely recognizabl...  Read More
by Corie Ralston
Optimizing the beamline
February 18th, 2020
Our footprinting beamline is getting a realignment this week, which should optimize the flux. It seems that over the years the various apertures have drifted a bit, and it is time for a tuneup. Below ...  Read More
by Corie Ralston
Visible light footprinting - is it possible?
February 8th, 2020
We have colleagues who user UV lasers to excite hydrogen peroxide to create hydroxyl radicals (this is the method called FPOP) but we were wondering if it might be possible to use visible light to do ...  Read More
by Corie Ralston
Some cool pictures of the beamline
January 11th, 2020
We snapped some colorful pictures of the x-ray footprinting hutch and beamline. The first is the interior of the hutch when an interlock is in progress. The red light warns people to get out of the hu...  Read More
by Corie Ralston